Study: Cancer drug substitute linked to higher rate of relapse

(CBS News) Abby Alonzo was 10 when she was diagnosed in 2009 with Hodgkin's lymphoma, a cancer of the immune system. With proper treatment, 90 percent of patients survive.

"It wasn't as hard for me as I think it as it was on my mom and my brother and my dad," Abby says.

Abby began a seven-drug regimen. But in 2010, doctors told Abby's mother, Katie, there was a nationwide shortage of one of the medicines -- mechlorethamine.

"I started to get a little hysterical, 'Why is it not available?'" says Katie.

In 2010, 23 cancer drugs had shortages. Reasons include manufacturing problems and low profit margins for the drugs, which became mostly generic, and therefore less expensive, than brand-name.

"There is really nothing you can do," Katie says. "You do what your doctor tells you to do, you take what medications your doctor tells you to take, and you pray that it works. And if one of those medications isn't available, you just take, you know, the next-best thing."

Doctors thought the next-best thing for patients like Abby was a drug called cyclophosphamide.

Life-saving cancer drugs for children stuck in federal legislative limbo

But a new study in the New England Journal of Medicine showed 88 percent treated with the original drug were cancer-free after two years -- compared to only 75 percent of those receiving the replacement drug.

"This is the first study to clearly show that when we substitute one drug for what we think is just an equally good drug, that's not always going to be the case. So it's demonstrating a negative impact on patients," says Dr. Richard Gilbertson, the director of cancer care at St. Jude Children's Research Hospital.

Abby was one of the patients who relapsed. She then needed a bone marrow transplant, radiation and more chemotherapy. Right now, she shows no signs of cancer.

"What if I relapsed again? Or what if something else happens? You know, it is just really scary, that part," Abby says.

The original drug in the study is finally available again after almost three years. But there are still 13 drugs used in cancer therapy, and a total of 100 on the FDA shortage list.

Congress passed legislation last July giving the FDA more authority to deal with cancer drug shortages. That new law has made a big difference, and the key provision is the requirement that drug manufacturers let the FDA know when there's an impending shortage.

Since that law was passed, there has been a doubling of those notifications, so the FDA can increase imports from abroad and tell other manufacturers in the United States to step up production.

Another provision in that law is that the FDA set up a task force looking at other possible solutions to the drug shortage crisis, and they're required to submit that report to Congress by this coming July.

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Toyota Agrees to $1B Settlement in Acceleration Case

Toyota has agreed to pay more than $1 billion to customers to settle a class action lawsuit that alleged its vehicles accelerated dangerously and without warning, according to statements by the carmaker and the plaintiffs' attorney.

The deal, which still needs approval by a federal judge in California, includes a $250 million fund to be paid to Toyota owners who sold their cars at a loss following reports of vehicle malfunctions, as well as the installation of a brake override system in about 3.25 million vehicles

An additional $250 million fund will be created to pay those owners whose vehicles are not eligible for the retrofitted brakes.

David Zalubowski/AP PHoto

Toyota recalled more than 14 million vehicles after reports of sudden, unexplained acceleration in several models began to surface between 2009 and 2010. There were also reports of brake problems with the Prius hybrid.

Toyota insists that it was not an electrical flaw that caused the acceleration problems, but driver error, floor mats and sticky gas pedals.

Both the National Highway Traffic Safety Administration and NASA have said there is nothing in wrong with programs that run the vehicles' onboard computers

"From the very start, this was a challenging case," said Steve Berman, the plaintiffs' lawyer. "We brought in automotive experts, physicists and some of the world's leading theoreticians in electrical engineering to help us understand what happened to drivers experiencing sudden acceleration."

The settlement also includes $30 million to be given to outside groups to study automotive safety.

In a statement, Toyota agreed to the deal.

"In keeping with our core principles, we have structured this agreement in ways that work to put our customers first and demonstrate that they can count on Toyota to stand behind our vehicles." said Toyota spokesman Christopher P. Reynolds.

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Mental illness, poverty haunted Afghan policewoman who killed American

KABUL (Reuters) - The Afghan policewoman suspected of killing a U.S. contractor at police headquarters in Kabul suffered from mental illness and was driven to suicidal despair by poverty, her children told Reuters on Wednesday.

The woman was identified by authorities as Narges Rezaeimomenabad, a 40-year-old grandmother and mother of three who moved here from Iran 10 years ago and married an Afghan man.

On Monday morning, she loaded a pistol in a bathroom at the police compound, hid it in her long scarf and shot an American police trainer, apparently becoming the first Afghan woman to carry out such an attack.

Narges also tried to shoot police officials after killing the American. Luckily for them, her pistol jammed. Her husband is also under investigation.

Her son Sayed, 16, and daughter Fatima, 13, described how they tried to call their parents 100 times after news broke of the shooting, then waited in vain for them to come home.

They recalled Narges's severe mood swings, and how at times she beat them and even pulled out a knife. But the children said she was consistent in bemoaning poverty.

"She was usually complaining about poverty. She was complaining to my father about our conditions. She was saying that my father was poor," Sayid said in an interview in their damp, cold two-room cement house.

On the floor beside him were his mother's prescriptions and a thick plastic bag filled with pills she tried to swallow to end the misery about a month ago. On another occasion, she cut her wrist with a razor, Sayed said.

"My father was usually calm and sometimes would say that she was guilty too because it wasn't a forced marriage. They fell in love and got married."

There was no sign in their neighborhood of the billions of dollars of Western aid that have poured into Afghanistan since the ouster of the Taliban in 2001, or of government investment.

RAW SEWAGE, STAGNANT WATER, DIRT ROADS

The lane outside their home stank of raw sewage.

Dirty, stagnant water filled holes in dirt roads nearby, where children in tattered clothes played and butchers stood by cow's hooves in shops choked by dust.

Afghanistan is one of the world's poorest nations, with a third of its 30 million residents living under the poverty line.

The sole distractions from the daily grind appeared to be a deck of playing cards and a compact disc with songs from Iranian pop singers, scattered on the floor of a room where Narges would lock herself in and weep, or sit in silence.

At times, Narges would try to focus on building her children's confidence, telling them to be guided by the Muslim holy book, the Koran, to tackle life's problems.

Sayed and Fatima said she never spoke badly of the U.S. presence in Afghanistan or of President Hamid Karzai's government.

Neighbor Mohammad Ismail Kohistani was dumbfounded to hear on the radio that Afghan officials were combing Narges' phone records to try to determine whether al Qaeda or the Taliban could have brainwashed her into carrying out a mission.

But he was acutely aware of her mental problems and often heard her scream at her husband, whose low-level job in the crime investigation unit of the police brought home little cash.

Kohistani, who operates a small sewing shop with battered machines, never imagined his neighbor could be accused of a high-profile attack that raised new questions about the direction of an unpopular war.

"I became very depressed and sad," said Kohistani, sitting on the floor few feet from a tiny wood-burning stove in Narges's home, alongside family photographs and a police training manual.

Fatima would often seek refuge in Kohistani's house when her mother's behavior became unbearable. "She did not hate us, but usually she was angry and would not talk to us," said Fatima, her eyes moist with tears.

Nevertheless, she missed her mother. The children were staying with a cousin.

"I ask the government to free my mother, otherwise our future will be destroyed," said Fatima.

Officials described it as another "insider shooting", in which Afghan forces turn on Westerners they are meant to be working with to stabilize the country. There have been over 52 such attacks so far this year.

The shooting at the police headquarters may have alarmed Afghanistan's Western allies. But some Afghans have grown numb to the violence.

Kohistani's 70-year-old father Omara Khan, who sports a white beard, sat twirling prayer beads beneath a photograph of Narges in a black veil beside one of her husband.

Asked what he thought of the attack, he laughed.

"This is common in Afghanistan," said Khan, who lived through decades of upheaval, including the 10-year Soviet occupation and a civil war that destroyed half of Kabul and killed some 50,000 civilians.

"People are killed every day."

(Editing by Ron Popeski)

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Nicaraguan farmers stay put despite volcano warning

CHINANDEGA, Nicaragua: Some 1,500 farmers living on the slopes of the San Cristobal volcano refused to leave, despite being ordered to evacuate as the volcano spewed gas, sand and ash.

"People have not evacuated because we do not want to go and leave the area abandoned," Maria Pereira told AFP.

Pereira lives in "Grecia 4", a community of about 600 people at the base of the volcano, in the Chinandega department.

She said columns of ash "bathed the trees, houses, and roads in white" and "pretty sand fell" in the morning. She said by early afternoon volcanic activity had decreased, though in the evening new columns of ash shot up.

In another community near the volcano, Bethlehem, some farmers resisted efforts of Civil Defence officials to convince them to obey the evacuation order.

Around 140 Civil Defence troops have been deployed to "persuade" farmers to move away from the danger zone, state deputy Colonel Nestor Solis told reporters.

The government issued a yellow alert on Wednesday, ordering the evacuation of 300 families living near the volcano.

Reiterating the evacuation order on Wednesday, first lady Rosario Murillo, a government spokeswoman, said "the situation of the volcano is unstable".

But she did not specify how many had obeyed the evacuation order or where they are being housed.

San Cristobal, the tallest of Nicaragua's seven active volcanoes, is believed to have erupted for the first time in 1685.

- AFP/al

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Tap Twitter, control a cockroach

Too bad we can't control all cockroaches through Twitter. Yuck.

(Credit:
Brittany Ransom)

Next time you see a cockroach, don't scurry away faster than it can flee. In fact, if you're a lover of the weirder side of life, the intrusive insect could represent one heck of a science project.

For example, artist Brittany Ransom created Twitter Roach -- a discoid cockroach that can be controlled through tweets that it receives on the popular microblogging service.

As it turns out, humans can actually control cockroaches with a device called RoboRoach -- a tiny electronic backpack that attaches to a cockroach and stimulates the bug's antenna nerves, enabling the controller to turn the insect left or right with the press of a button.

Ransom built upon the Roboroach concept and added some Arduino hardware and custom-programmed software to link the bug to Twitter. While on display at the "Life, in some form" art exhibition by the Chicago Artists Coalition, visitors could send the @TweetRoach account commands such as "#TweetRoachLeft" and #TweetRoachRight."

The Tweet Roach sits while awaiting its next command.

(Credit:
Brittany Ransom)

Those of you concerned about insect welfare can rest easy; the roach didn't stay enslaved all day long. Ransom told Crave via e-mail that the bug "wears the backpack for short intervals" and "is only accessible to the Twitter community during designated times." To avoid a flood of commands, Ransom set the cockroach to receive no more than one tweet every 30 seconds.

Why would someone take on such a strange project? Ransom says she's exploring a kind of insectoid parallel to the digital overstimulation many of us experience today. She aims to see if the cockroach can learn to eventually learn to adapt and ignore the stimulating effects of her setup.

"At what point does its intelligence and ability take over? How much does it take before we are all desensitized to overstimulation? As we, as human beings, grow more cyborgian and interconnected through social media, this project helps us participate in discovering the answer," Ransom said in an e-mail about the project.

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Newtown's Christmas: Inspiration amid the grief

NEWTOWN, Conn. Newtown observed Christmas amid snow-covered teddy bears, stockings, flowers and candles left in memory of the 20 children and six educators gunned down at an elementary school just 11 days before the holiday.

Volunteers were keeping watch over a candlelight vigil scheduled to last all Christmas day in the Connecticut town.

Twenty-six candles, one for each victim, were lit at midnight Monday near a huge sidewalk memorial filled with teddy bears, flowers, candles, posters and other tributes to the dead.

Volunteers were taking three-hour shifts Tuesday to ensure they remain burning.

Police officers from other communities were filling in for Newtown police so they could have the holiday off.

"It's a nice thing that they can use us this way," Ted Latiak, a police detective from Greenwich, Conn., said Christmas morning, as he and a fellow detective, each working a half-day shift, came out of a store with bagels and coffee for other officers.

And well-wishers from around the country continued visiting the town to pay their respects.

At Christmas morning services, congregants were told that good always overcomes evil.

The pastor of a church in Newtown, Conn., that was attended by eight of the child victims of the Sandy Hook Elementary School shooting told parishioners that this Christmas Day "is the day we begin everything all over again."

The Rev. Robert Weiss spoke at the second of four Masses at St. Rose of Lima Roman Catholic Church.

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Newtown first responders: Don't call us heroes

Recalling the events of eleven days ago, Weiss said, "The moment the first responder broke through the doors, we knew good always overcomes evil."

Today, he says, "We know Christmas in a way we never ever thought we would know it."

The outpouring of support for this community was evident on Christmas Eve, with visitors arriving at town hall with offerings of cards, handmade snowflakes and sympathy.

"We know that they'll feel loved. They'll feel that somebody actually cares," said Treyvon Smalls, a 15-year-old from a few towns away who arrived bearing hundreds of cards and paper snowflakes collected from around the state.

An overflow crowd of several hundred people attended Christmas Eve services at Trinity Episcopal Church in Newtown. They were greeted by the sounds of a children's choir, in a sanctuary hall decorated with green wreaths and red bows.

The Trinity Church program said flowers were donated in honor of Sandy Hook shooting victims, identified by name or as the "school angels" and "Sandy Hook families."

36 Photos

Vigils for Conn. school shooting victims

The service, which generally took on a celebratory tone, made only a few vague references to the shooting. Pastor Kathie Adams-Shepherd led the congregation in praying "that the joy and consolation of the wonderful counselor might enliven all who are touched by illness, danger, or grief, especially all those families affected by the shootings in Sandy Hook."

Police say the gunman, Adam Lanza, killed his mother in her bed before his Dec. 14 rampage and committed suicide as he heard officers arriving. Authorities have yet to give a theory about his motive.

While the grief is still fresh, some residents are urging political activism. A group called Newtown United has been meeting at the library to talk about issues ranging from gun control, to increasing mental health services to the types of memorials that could be erected for the victims. Some clergy members have said they also intend to push for change.

15 Photos

U.S. gun shops report spike in sales

"We seek not to be the town of tragedy," said Rabbi Shaul Praver of Congregation Adath Israel. "But, we seek to be the town where all the great changes started."

Since the shooting, messages similar to the ones delivered Monday have arrived from around the world. People have donated toys, books, money and more. A United Way fund, one of many, has collected $3 million. People have given nearly $500,000 to a memorial scholarship fund at the University of Connecticut.

In the center of Newtown's Sandy Hook section Monday, a steady stream of residents and out-of-towners snapped pictures, lit candles and dropped off children's gifts at an expansive memorial filled with stuffed animals, poems, flowers, posters and cards.

"All the families who lost those little kids, Christmas will never be the same," said Philippe Poncet, a Newtown resident originally from France. "Everybody across the world is trying to share the tragedy with our community here."

Richard Scinto, a deacon at St. Rose of Lima Roman Catholic Church, said the church's pastor, Rev. Robert Weiss, used several eulogies this week to tell his congregation to get angry and take action against what some consider is a culture of gun violence in the country.

Praver and Scinto said they are not opposed to hunting or to having police in schools, but both said something must be done to change what has become a culture of violence in the United States.

"These were his mother's guns," Scinto said. "Why would anyone want an assault rifle as part of a private citizen collection?"

A mediator who worked with Lanza's parents during their divorce has said Lanza, 20, was diagnosed with Asperger's syndrome, an autism-like disorder that is not associated with violence. It is not known whether he had other mental health issues. The guns used in the shooting had been purchased legally by his mother, Nancy Lanza, a gun enthusiast.

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Gunman Killed Firemen With Bushmaster, Left Note

A convicted killer, who shot dead two firefighters with a Bushmaster assault rifle after leading them into an ambush when they responded to a house fire he set in Western New York, left behind a typewritten note saying he wanted to "do what I like doing best, killing people," police said.

William Spengler, 62, set his home and a car on fire early Monday morning with the intention of setting a trap to kill firefighters and to see "how much of the neighborhood I can burn down," according to the note he wrote and which police found at the scene. The note did not give a reason for his actions.

Spengler, who served 18 years in prison for beating his 92-year-old grandmother to death with a hammer in 1981, hid Monday morning in a small ditch beside a tree overlooking the sleepy lakeside street in Webster, N.Y., where he lived with his sister, police said today in a news conference.

Police said they found remains in the house, believed to be that of the sister, Cheryl Spengler, 67.

As firefighters arrived on the scene after a 5:30 a.m. 911 call on the morning of Christmas Eve, Spengler opened fire on them with the Bushmaster, the same semi-automatic, military-style weapon used in the Dec. 14 rampage killing of 20 children in Newtown, Conn.

"This was a clear ambush on first responders… Spengler had armed himself heavily and taken area of cover," said Gerald Pickering, the chief of the Webster Police Department.

Armed with a Smith & Wesson .38 caliber revolver, a Mossman 12-gauge shotgun, and the Bushmaster, Spengler killed two firefighters, and injured two more as well as an off-duty police officer at the scene.

As a convicted felon, Spengler could not legally own a firearm and police are investigating how he obtained the weapons.

One firefighter tried to take cover in his fire engine and was killed with a gunshot through the windshield, Pickering said.

Responding police engaged in a gunfight with Spengler, who ultimately died, likely by a self-inflicted gunshot wound to the head.

As police engaged the gunman, more houses along Lake Ontario were engulfed, ultimately razing seven of them. Some 33 people in adjoining homes were displaced by the fire.

SWAT teams were forced to evacuate residents using armored vehicles.

Police identified the two slain firefighter as Lt. Michael Chiapperini, a 20-year veteran of the Webster Police Department and "lifetime firefighter," according to Pickering, and Tomasz Kaczowka, who also worked as a 911 dispatcher.

Two other firefighters were wounded and remain the intensive care unit at Strong Memorial Hospital in Rochester, N.Y.

Joseph Hofsetter was shot once. He sustained an injury to his pelvis and has "a long road to recovery," said Dr. Nicole A. Stassen, a trauma physician.

The second firefighter, Theodore Scardino, was shot twice and received injuries to his left shoulder and left lung, as well as a knee.

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Egypt approves constitution drafted by Mursi allies

CAIRO (Reuters) - Egyptian voters overwhelmingly approved a constitution drafted by President Mohamed Mursi's allies, results announced on Tuesday showed, proving that liberals, leftists and Christians have been powerless to halt the march of Islamists in power.

Final elections commission figures showed the constitution adopted with 63.8 percent of the vote in the referendum held over two days this month, giving Mursi's Islamists their third straight electoral victory since veteran autocrat Hosni Mubarak was toppled in a 2011 revolution.

Opposition groups had taken to the streets to block what they see as a move to ram through a charter that mixes politics and religion dangerously and ignores the rights of minorities.

Mursi says the text - Egypt's first constitution since Mubarak's fall - offers enough protection for minorities, and adopting it quickly is necessary to end two years of turmoil and political uncertainty that has wrecked the economy.

"I hope all national powers will now start working together now to build a new Egypt," Murad Ali, a senior official in the Muslim Brotherhood's Freedom and Justice Party, told Reuters.

"I see this as the best constitution in Egypt's history."

In a sign that weeks of unrest have taken a further toll on the economy, the government ordered new restrictions on foreign currency apparently designed to prevent capital flight. Leaving or entering with more than $10,000 cash is now banned.

Two years since waves of unrest broke out across the Middle East and North Africa - sweeping away long-entrenched rulers in Tunisia, Libya and Yemen as well as Egypt - well-organized Islamist parties have emerged as the main beneficiaries.

Urban secularists and liberals who were behind the revolts complain that their success has been hijacked.

"We need a better constitution," said Khaled Dawood, an opposition spokesman. "It does not represent all Egyptians."

Mursi's opponents say the new constitution could allow clerics to intervene in lawmaking, while offering scant protections to minorities and women. Mursi dismisses those criticisms, and many Egyptians are fed up with street protest movements that have prevented a return to normality.

Immediately after the announcement, a small group of protesters set tires on fire and blocked traffic near the central Tahrir square, the cradle of Egypt's uprising, but there were no immediate signs of violence or major demonstrations.

Washington, which provides billions of dollars a year in military and other support for Egypt and regards it as a pillar of security in the Middle East, called on Egyptian politicians to bridge divisions and on all sides to reject violence.

"President Mursi, as the democratically elected leader of Egypt, has a special responsibility to move forward in a way that recognizes the urgent need to bridge divisions," State Department spokesman Patrick Ventrell said. He noted that many Egyptians had voiced "significant concerns" over the constitutional process.

WORSENING ECONOMY

The government says its opponents are worsening the economic crisis by prolonging political upheaval. It has pledged to impose unpopular tax increases and spending cuts to win a loan package from the International Monetary Fund.

The ban on travelling with more than $10,000 in cash followed a pledge by the central bank to take unspecified measures to protect Egyptian banks. Some Egyptians have begun withdrawing their savings in fear of more restrictions.

"I am not going to put any more money in the bank and neither will many of the people I know," said Ayman Osama, father of two young children.

He said he had taken out the equivalent of about $16,000 from his account this week and planned to withdraw more, adding that he had also told his wife to buy more gold jewellery.

The "yes" vote paves the way for a parliamentary election in about two months, setting the stage for another battle between surging Islamists and their fractious opponents.

The final result, announced by the election commission, matched - to the last decimal place - an earlier unofficial tally announced by Mursi's Muslim Brotherhood.

But the opposition said it was disappointed - it had appealed for the result to be amended to reflect what it described as major vote violations during the two-round vote.

Officials said there were no violations serious enough to change the result significantly. "We have seriously investigated all the complaints," said judge Samir Abu el-Matti of the Supreme Election Committee. The final turnout was 32.9 percent.

SENSE OF CRISIS

The referendum has sharpened painful divisions in the Arab world's most populous nation and a growing atmosphere of crisis has gripped Egypt's polarized society.

Anxiety about the economy deepened this week when Standard and Poor's cut Egypt's long-term credit rating. Prime Minister Hisham Kandil told the nation of 83 million on Tuesday the government was committed to fixing the economy.

"The main goals that the government is working towards now is plugging the budget deficit, and working on increasing growth to boost employment rates, curb inflation, and increase the competitiveness of Egyptian exports," he said.

The referendum follows Islamist victories in parliamentary and presidential elections, representing a decisive shift in a country at the heart of the Arab world where Mursi's Muslim Brotherhood was suppressed for generations by military rulers.

However, secularist and liberal opposition members hope they can organize better in time for the next parliamentary vote.

Hossam El-Din Ali, a 35-year-old newspaper vendor in central Cairo, said he agreed the new constitution would help bring some political stability but like many others he feared the possible economic austerity measures lying ahead.

"People don't want higher prices. People are upset about this," he said. "There is recession, things are not moving. But I am wishing for the best, God willing."

(Additional reporting by Patrick Werr, Tamim Elyan, Ahmed Tolba and Marwa Awad; Writing by Maria Golovnina)

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China and emerging powers to pay more for UN

UNITED NATIONS: China, Brazil, India and other emerging powers agreed to major increases in their United Nations payments as the global body hammered out a new budget deal this week to avoid its own fiscal cliff.

The boom countries will pay more as economic crisis allows European nations, such as Britain, Germany and France and Japan to cut their contributions.

While the sums involved are not huge by global standards -- the revised UN budget for 2012-2013 is $5.4 billion -- diplomats say the new shareout is a snapshot of the world's changing economic fortunes.

And the UN system has maintained sum of its quirks with Greece, despite its economic slump, still paying more than India, which aspires to become a permanent member of the UN Security Council.

UN contributions are worked out according to a country's share of global gross national income (GNI). China will pay an extra 61 per cent in UN fees, taking its share of the budget from 3.2 to 5.1 per cent. It will overtake Canada and Italy to become the sixth biggest UN contributor.

Brazil has agreed to an 82 per cent hike in payments. It will pay 2.9 per cent of the budget instead of 1.6 per cent. India's payments will increase 24 per cent, taking its budget share from 0.5 to 0.66 per cent. And Russia's payments will go up by 52 per cent.

The United States remains the major UN financier, though its contributions are pegged at 22 per cent while it accounts for 24.2 per cent of world GNI.

Other major contributors will all see payments decrease. Japan, in second place, will see a 13.5 per cent drop to 10.8 per cent of the budget. It previously accounted for 12.5 per cent of UN finances.

Germany's share of the budget will fall from 8.0 to 7.1 per cent, France from 6.1 to 5.6 per cent and Britain from 6.6 to 5.18 per cent.

"This is a start brought on by the economic crisis in Europe, but there will have to be more changes eventually," said one western diplomat.

Another noted the new payment breakdown reflects changes around the world, and that the contrast between Greece and India was "striking."

Greece's share of budget will decrease from 0.7 to 0.64 per cent. But its share of global GNI is 0.5 per cent, while India, which pays about the same amount, accounts for 2.2 per cent of world GNI.

A complicated series of rebates allows various countries to claim reductions in payments. China and the other emerging powers still pay less than their share of the world economy. The Europeans and Japan still pay more.

The UN's regular budget does not include its peacekeeping operations, which cost more than $7.5 billion a year and are paid for with separate assessments.

Under the deal agreed this week, a pay freeze has been ordered for the estimated 10,000 UN staff in New York.

- AFP/ck

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Stuxnet attacks Iran again, reports say

An Iranian news agency says the country successfully fended off yet another attack by the Stuxnet worm, according to reports.

The cyberattack targeted a power plant and other sites in southern Iran over the fall, the BBC and the Associated Press reported today.

Discovered in June 2010, Stuxnet is believed to be the first malware targeted specifically at critical infrastructure systems. It's thought to have been designed to shut down centrifuges at Iran's Natanz uranium enrichment plant, where stoppages and other problems reportedly occurred around that time. The sophisticated worm spreads via USB drives and through four previously unknown holes, known as zero-day vulnerabilities, in Windows.

Stuxnet is just one of several versions of malware aimed at Middle Eastern countries in the past two and a half years. Along Stuxnet, there have arisen Duqu, Gauss, Mahdi, Flame, Wiper, and Shamoon.

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